METABOLIC DISORDER

Hyperlipoproteinemia

Hyperlipoproteinemia is a disease in which the body is unable to properly break down lipids and lipoproteins, mainly cholesterol and triglycerides. As a result, their levels are continually elevated in the blood which poses a serious health threat. Hyperlipoproteinemia can be primary (genetic) or secondary (idiopathic) and it has been associated with increased risk from heart disease.

Gangliosidosis in Cats: Genetic Disease Explained

Gangliosidosis is a group of lipid storage disorders characterized by the accumulation of lipids – gangliosides in neurons. The disease was identified both in humans and cats. Human gangliosidosis is classified into two types, GM1 and GM2. The second type is further classified into three subtypes: GM2A (Tay-Sachs disease), GM2AB (AB variant) and GM2B (Sandhoff disease or 0 variant). All of the variants of the human disease have been identified in cats except for the Tay-Sachs (GM2A).

Cystinuria in Cats: What Do I Need to Know?

Cystinuria is an inherited metabolic disease that is relatively common in dogs, but rare in cats (Mizukami, 2016). The condition is characterized by defective amino acid reabsorption, leading to the formation of cystine stones in the kidney, ureter and the bladder (cystine urolithiasis). This can lead to urinary obstruction. In cats, only two cystinuria types have been identified so far: I-A and II-B (Mizukami et al, 2015 & Mizukami et al, 2016).