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Has your cat been diagnosed with polycystic kidney disease? You are not alone. Polycystic kidney disease (PKD) affects up to 6% of all cats. Many cats with PKD will live long, happy lives despite having cysts in their kidneys. Unfortunately, some cats develop more or larger cysts than other PKD cats, and this can lead to chronic renal disease and kidney failure. It’s best to identify and treat this feline disease as soon as possible.